Extended Data Fig. 3: Data-driven thresholds to partition interactions into neutral, negative and positive interactions for analysis.

C0, C− and C+ correspond to classes of neutral, negative and positive genetic regulatory interactions. Distance between C0and C− (\(W\left( {g_0,g_ - ,\theta _ - ,\theta _ + } \right)\), solid green), and C0 and C+ (\(W\left( {g_0,g_ + ,\theta _ - ,\theta _ + } \right)\), solid blue), number of claims in C−, dotted green, number of claims in C+, dotted blue) for GeneWays (a) and Literome (b). Distance between C0 and C− (\(W\left( {g_0,g_ - ,\theta _ - ,\theta _ + } \right)\)) in GeneWays (c) and Literome (d); Distance between C0 and C+ (\(W\left( {g_0,g_ + ,\theta _ - ,\theta _ + } \right)\)) in GeneWays (e) and Literome (f).