Extended Data Fig. 3: Urinary metabolic reaction network maps highlighting the expression of the dietary metabotype of individual participants in response to Diet 1 and Diet 4 ordered by participant number. | Nature Food

Extended Data Fig. 3: Urinary metabolic reaction network maps highlighting the expression of the dietary metabotype of individual participants in response to Diet 1 and Diet 4 ordered by participant number.

From: RETRACTED ARTICLE: Dietary metabotype modelling predicts individual responses to dietary interventions

Extended Data Fig. 3

A, participant 1 (entropy = 90.50), B, participant 2 (entropy = 90.04), C, participant 3 (entropy = 101.76), D, participant 4 (entropy = 95.49), E, participant 5 (entropy = 96.55), F, participant 7 (entropy = 106.37), G, participant 8 (entropy = 84.46), H, participant 9 (entropy = 81.69). The size of coloured nodes is proportional to the fold-change of that metabolite for that person. The colours of the edges are related to the sum of fold-changes of each pair of metabolites connected via their shortest path (fewest number of chemical reactions – see Methods). The more disordered (high entropy), or metabolically flexible, a subnetwork is, the stronger the associated edge weights (yellow-orange) in contrast to less perturbed pathways (magenta-blue edge weights). Entropy is expressed in arbitrary units.

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