Extended Data Fig. 4: Urinary metabolic reaction network maps highlighting the expression of the dietary metabotype of individual participants in response to Diet 1 and Diet 4 ordered by participant number. | Nature Food

Extended Data Fig. 4: Urinary metabolic reaction network maps highlighting the expression of the dietary metabotype of individual participants in response to Diet 1 and Diet 4 ordered by participant number.

From: RETRACTED ARTICLE: Dietary metabotype modelling predicts individual responses to dietary interventions

Extended Data Fig. 4

A, participant 10 (entropy = 81.92), B, participant 11 (entropy = 95.31), C, participant 12 (entropy = 80.13), D, participant 13 (entropy = 84.06), E, participant 14 (entropy = 78.81), F, participant 15 (entropy = 106.53), G, participant 17 (entropy = 76.12), H, participant 18 (entropy = 95.74), I, participant 19 (entropy = 92.33). The size of coloured nodes is proportional to the fold-change of that metabolite for that person. The colours of the edges are related to the sum of fold-changes of each pair of metabolites connected via their shortest path (fewest number of chemical reactions – see Methods). The more disordered (high entropy), or metabolically flexible, a subnetwork is, the stronger the associated edge weights (yellow-orange) in contrast to less perturbed pathways (magenta-blue edge weights). Entropy is expressed in arbitrary units.

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