Extended Data Fig. 5: NSCLC overall and progression-free survival based on the presence of motif neoepitopes in all supertypes.
Survival estimated using the Kaplan-Meier method and compared between groups with a non-parametric log-rank test. Dashed lines represent medians. Motif neoepitopes required a radical substitution in the anchor position with a known C-terminus (see Methods), survival curves depicted in blue. The survival curves of those without motif neoepitopes are depicted in red. a, Patients with at least one motif neoepitope (N = 28 patients) had a median OS of 12.6 vs 5.2 months in those without (N = 10 patients), P=0.013. b, Patients with at least one motif neoepitope (N = 28 patients) had a median PFS of 5.6 vs 6.3 months in those without (N = 10 patients), P=0.120.
