Extended Data Fig. 5: Modular transcriptional fingerprints for group comparison (Cohort 1).
Responsive modules at each time point in comparison to baseline are mapped on a grid for visualization purposes. The color of the spots indicates the direction of changes in transcript abundancies: red for up-regulation and blue for down-regulation. The degree of intensity of the spots denotes the level of activation, which is given by the proportion of transcript coherently regulated. A legend is provided with functional interpretations indicated at each position of the grid by a color code (N = 12 cohort and N = 11 cohort 2).
