Extended Data Fig. 6: Mapping perturbations of the modular repertoire across individual samples. | Nature Cancer

Extended Data Fig. 6: Mapping perturbations of the modular repertoire across individual samples.

From: Flt3 ligand augments immune responses to anti-DEC-205-NY-ESO-1 vaccine through expansion of dendritic cell subsets

Extended Data Fig. 6

The responsive modules in individual subjects from cohort 1 (N = 12) after treatment as compared to baseline are mapped into grids. The expression profile of each individual subject was calculated as a FC and difference after treatment as compared to the expression of individual samples at baseline. To determine changes in individual subjects, a cut-off is set against which individual genes constitutive of a module are tested (|FC|> 1.5 and |difference|>100).

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