Extended Data Fig. 3: Urod depletion induces an immune suppressive and pro-tumorigenic transcriptional program in LLC cells.
From: eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer
a-b, Gene Set Enrichment Analysis highlighting expression of top gene sets significantly increased in LLC cells expressing Urod shRNA. c, Ingenuity Pathway Analysis demonstrating a decrease in expression of genes involved in immune cell recruitment and migration. Graph represents biological processes plotted against their bias adjusted z-scores. Transcriptional analysis was performed on n = 3 biological replicates per group.
