Extended Data Fig. 4: Rel gene deletion in MDSCs leads to upregulated expression of inflammatory genes and decreased Cebpb downstream genes.
From: c-Rel is a myeloid checkpoint for cancer immunotherapy
a,b, Results from Ingenuity Pathway analysis of the RNA-seq data of bone marrow-derived WT and Rel−/− MDSCs, showing upregulated ‘inflammatory response’ genes (a, red) and downregulated Cebpb downstream genes (b, green) in Rel−/− MDSCs. Statistical significance was determined by calculated a right-tailed Fisher’s Exact Test. All data are pooled from 3 independent experiments.
