Extended Data Fig. 6: Zeb2 expression and intestinal barrier integrity in the small intestine. | Nature Cancer

Extended Data Fig. 6: Zeb2 expression and intestinal barrier integrity in the small intestine.

From: Zeb2 drives invasive and microbiota-dependent colon carcinoma

Extended Data Fig. 6

Quantitative PCR analysis for expression of tight junction proteins (Claudin-4, -6 and -7, Occludin, Tjp-1, F11R/JAM-1) and desmosomes (Desmocollin-1 and -3, Desmoglein-2, Plakophillin-1) in lysates from the small intestine of Zeb2IEC-Tg/+ (Tg/+, n=6 mice) and wild-type littermate controls (WT, n=5 mice). Data are presented as mean ± SEM and were analyzed with two-tailed Mann Whitney test. *, p-value = 0.0173; ** p-value = 0.0043; ns, non-significant.

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