Extended Data Fig. 9: ABX treated Zeb2IEC-Tg/+ mice are protected from CRC development.
From: Zeb2 drives invasive and microbiota-dependent colon carcinoma
a, Clinical stool score of untreated (n=6 mice), vancomycin-treated (n=6 mice) and aztreonam-treated (n=4 mice) Zeb2IEC-Tg/+ mice based on Hemoccult assay. Data are presented as mean ± SEM. b, Colon pathology detected by endoscopy and represented as MEICS (murine endoscopic index of colitis severity) score. Each symbol represents one mouse. Data are presented as mean ± SEM. c, Colon histology of Aztreonam (left panel) and Vancomycin (right panel) treated Zeb2IEC-Tg/+ mice by H&E staining. Scale bar: 200µm. Representative images from one experiment with n=4 mice.
