Extended Data Fig. 7: Single cell RNA sequencing lineage analysis.
Series of t-SNE plots of n = 448 untreated and n = 163 treated cells showing the positive (TRUE) or negative (FALSE) assignment of each lineage across different regions of the plot. Each cell is colored in red if it expresses genes associated with the named lineage (>0.75 average z-score over genes in the signature) or in grey if it does not express the signature or expresses it below the cut-off level. The plots do not show relative expression levels but aim to highlight how the same cell can have concomitantly high expression of gene markers characteristic of different lineages.
