Extended Data Fig. 2: Sequence diversity of peptides presented by HLA class I alleles. | Nature Cancer

Extended Data Fig. 2: Sequence diversity of peptides presented by HLA class I alleles.

From: Negative trade-off between neoantigen repertoire breadth and the specificity of HLA-I molecules shapes antitumor immunity

Extended Data Fig. 2

Amino acid preference was determined at different peptide positions bound by each of the 67 investigated HLA class I alleles. Sequence logos were visualized for 9 amino acid long peptides only84. Alleles are ordered according to their promiscuity level. The vertical axes indicate the information content of the given position in bits. The relative sizes of characters are proportional to their frequency at the given position.

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