Extended Data Fig. 3: CGI hypermethylation levels show a broad range across T-ALL samples. | Nature Cancer

Extended Data Fig. 3: CGI hypermethylation levels show a broad range across T-ALL samples.

From: Acute lymphoblastic leukemia displays a distinct highly methylated genome

Extended Data Fig. 3

a) Genome browser tracks for WGBS data of representative precursor B cells and B-ALL subtypes for an exemplary locus (PAX6 gene; chr11:31,806,145-31,844,510, same as in Fig. 3b). Cancer samples show CGI hypermethylation in comparison to their respective healthy tissue to different extents. b) Violin plots showing the distribution of methylation in variably methylated CGIs (n = 9,349, determined based on all healthy and ALL samples) for every healthy and ALL sample within our cohort. White dots denote the median.

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