Extended Data Fig. 6: Tumour Vδ1 T cells demonstrate no evidence of clonotypic responses.
From: A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer
A) Repertoire analysis by normalised Shannon entropy (S.E.) of Vδ1 T cells in NT tissue (Tis) and paired lung tumours (Tum) calculated on TCRδ CDR3 amino-acid sequences. Wilcoxon matched-pairs signed rank test. B) Repertoire analysis by D50 of Vδ1 T cells in NT tissue (Tis) and paired lung tumours (Tum) calculated on TCRδ CDR3 amino-acid sequences. Wilcoxon matched-pairs signed rank test. C) Relative expression (TPM) of functional TCRγ Vγ genes in sorted intra- tumoural Vδ1 T cells from 5 patients and Vδ2 from 3 patients. All datapoints represent independent patients.
