Extended Data Fig. 3: Gating strategy and Gene Ontology analysis of FACS-based CRISPR/Cas9 screen. | Nature Cancer

Extended Data Fig. 3: Gating strategy and Gene Ontology analysis of FACS-based CRISPR/Cas9 screen.

From: P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia

Extended Data Fig. 3

a) Scatter-plot depicting gating strategy to isolate live sgRNA library transduced OCI-AML2 cells based on forward-scatter (FSC) and side-scatter (SSC). b) Scatter-plot depicting gating strategy to isolate singlet sgRNA library transduced OCI-AML2 cells based on FSC. c) Gene ontology (GO) analysis table of scoring genes enriched in the bottom sort (FSGS of > 1.5). P values calculated by Enrichr using Benjamini-Hochberg correction for multiple hypothesis testing.

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