Extended Data Fig. 7: Dynamics of CD4 T cell subsets following treatment.
a-c, Comparison of the frequency of Tregs (a), other Th (b) and naïve (c) CD4 T cells in all CD4 T cells from pre- and post-treatment responsive and non-responsive tumors. Data were summarized from n = 20, 15, 22, 7, 53, 22, 12, 4 and 7 tumor samples from datasets 1-9, respectively. R, responsive; NR, non-responsive; MPR, major pathologic response. Each dot represents one sample while the center line indicates the median value. The lower and upper hinges represent the 25th and 75th percentiles, respectively, and whiskers denote 1.5× interquartile range.
