Extended Data Fig. 7: melanoma patients data provides mechanistic link between anti-tumor activity of anti-CTLA-4 treatment in mice and humans. | Nature Cancer

Extended Data Fig. 7: melanoma patients data provides mechanistic link between anti-tumor activity of anti-CTLA-4 treatment in mice and humans.

From: Anti-CTLA-4 antibodies drive myeloid activation and reprogram the tumor microenvironment through FcγR engagement and type I interferon signaling

Extended Data Fig. 7

(a–d) Gene set enrichment analysis (GSEA) for responder vs non-responder patients. Green line shows running enrichment score for indicated gene ontology (GO) terms. All gene log2 fold-changes are ranked (bottom, grey) and genes belonging to the gene set are shown in black (top).

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