Extended Data Fig. 3: Migration of immune cells induced by OV-Cmab-hCCL5. | Nature Cancer

Extended Data Fig. 3: Migration of immune cells induced by OV-Cmab-hCCL5.

From: Specific targeting of glioblastoma with an oncolytic virus expressing a cetuximab-CCL5 fusion protein via innate and adaptive immunity

Extended Data Fig. 3

NK cells, macrophages, CD4+ T cells, and CD8+ T cells in the upper chamber induced by OV-Cmab-hCCL5- or OV-Q1-infected U251T2 GBM cells at an MOI of 2 in the lower chamber, measured by transwell assay. 72 hours after the transwell assay was set up, immune cells in the lower chamber were quantified by flow cytometry. Error bars indicate the standard deviations (s.d.) and data are presented as mean ± s.d.. Statistical analyses were performed by one-way ANOVA with P values corrected for multiple comparisons by Bonferroni method (n = 3 independent donors).

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