Extended Data Fig. 3: Baseline clinical characteristics of COSINR cohort.

(a) Association of clinicopathologic variables with progression-free (top) and overall survival (bottom). (b) Progression-free and overall survival of entire cohort by treatment arm. Dotted vertical lines represent median survival; two-sided Log-rank test. (c) Progression-free and overall survival by treatment arm in the subset of patients used for molecular analysis; two-sided Log-rank test; dotted lines represent median survival (n = 22 patients).