Extended Data Fig. 9: Protein and RNA expression of genetically modified breast cancer cells. | Nature Cancer

Extended Data Fig. 9: Protein and RNA expression of genetically modified breast cancer cells.

From: A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling

Extended Data Fig. 9

a. Relative gene expression analysis of CPT1A in human (MCF10A H-RasV12 and MCF7), mouse (4T1, EO771-MCB3 and EMT6.5) breast cancer cells infected with either a control shRNA, or two different CPT1A, or Cpt1a shRNAs normalized to the control condition. Data are presented as mean ± SD (n = 3 biological replicates). Unpaired two-tailed t-tests. b. Protein expression in mouse 4T1 cancer cells infected with either a non-targeting sgScrambled as a control or two different sgRNA against Cpt1a and Kat2a gRNAs. A representative of n = 3 experiments is shown.

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