Extended Data Fig. 10: MS/MS validation of lipids detected in metastases by MALDI-MSI molecular imaging. | Nature Cancer

Extended Data Fig. 10: MS/MS validation of lipids detected in metastases by MALDI-MSI molecular imaging.

From: A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling

Extended Data Fig. 10

a. MS/MS spectrum of the ion at m/z 760.5842 detected from the metastatic areas within the lung tissue in positive ion mode using the timsTOF fleX. Ions supporting the assignment of PC O-18:1_16:0 are annotated with their corresponding mass accuracy. b. MS/MS spectrum of the ion at m/z 760.5842 detected from the metastatic areas within the lung tissue in positive ion mode using the timsTOF fleX. Ions supporting the assignment of PC 20:1_16:0 are annotated with their corresponding mass accuracy. c. MS/MS spectrum of the ion at m/z 760.5842 detected from the metastatic areas within the lung tissue in positive ion mode using the timsTOF fleX. Ions supporting the assignment of PC18:1_16:0 are annotated with their corresponding mass accuracy.

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