Extended Data Fig. 7: Retinoic acid signaling in adipocytes and macrophages.
From: Endothelial Notch1 signaling in white adipose tissue promotes cancer cachexia
a,b, RT-qPCR analysis of Ucp1 (a) and beiging markers (b) in SVF-differentiated adipocytes treated with 0 nM (DMSO only), 10 nM, 100 nM or 1 µM ATRA for 24 hours (n = 3 biologically independent experiments). c, RT-qPCR analysis of Arg1 in BMDMs treated with ATRA for 72 hours (n = 3 biologically independent experiments). d, RT-qPCR analysis of Arg1 and Mrc1 in BMDMs treated with recombinant IL-33 for 72 hours (n = 3 biologically independent experiments). Data shown represent mean ± SEM, 1-way ANOVA (a), 2-way ANOVA (b) or unpaired two-sided t-test with Welch correction (c,d).
