Extended Data Fig. 4: Cell surface U5 snRNP200 expression on inversion(3) AML patient samples and human patient-derived cell lines. | Nature Cancer

Extended Data Fig. 4: Cell surface U5 snRNP200 expression on inversion(3) AML patient samples and human patient-derived cell lines.

From: Systematic evaluation of AML-associated antigens identifies anti-U5 SNRNP200 therapeutic antibodies for the treatment of acute myeloid leukemia

Extended Data Fig. 4

(a) UMAP overlay comparing normal donor (blue islands) and AML samples for identification of malignant AML cells (top panel, yellow cell islands; bottom panel, orange cell islands) and colorimetric overlays of CD34, CD33, U5 snRNP200, and CD32A. (b) Histograms of U5 snRNP200 expression on U937 cells versus three distinct human inversion(3) AML cell lines (HNT-34, MUTZ3, and YCU-AML1).

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