Extended Data Fig. 4: Malat1 controls the expression of immunoregulatory and Wnt signaling genes.
From: LncRNA Malat1 suppresses pyroptosis and T cell-mediated killing of incipient metastatic cells
a, WT and Malat1 KO 4T1 were subjected to bulk RNA-seq. Heatmap represents the top 50 DEGs (differentially expressed genes) in WT versus Malat1 KO 4T1 cells. b, RT-qPCR analysis of the expression of the indicated genes from the list of top DEGs (n = 3 independent experiments). c, Hallmark gene set enrichment analysis (GSEA) of bulk RNA-seq data from WT versus Malat1 KO 4T1 cells. d, KEGG-DEG relationship network. Data are presented as mean values +s.e.m (b).
