Extended Data Fig. 3: Correlation of Bcl-xl, BAK and MCL1 protein or mRNA expression to BRD-810 sensitivity in breast cancer cell lines. | Nature Cancer

Extended Data Fig. 3: Correlation of Bcl-xl, BAK and MCL1 protein or mRNA expression to BRD-810 sensitivity in breast cancer cell lines.

From: BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models

Extended Data Fig. 3

The expression level ratio of Bclxl and BAK protein (A) or mRNA (B), or MCL1 protein (C) or mRNA (D) was correlated to the sensitivity of breast cancer cell lines. Data is shown as linear regression with 95% CI (n = 19 cell lines).

Source data

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