Extended Data Fig. 3: Germline mutations and patient 1 and 6 WES results.
From: Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors
a, IGV tracks for the patients harboring germline variants, showing the germline EGFR mutations in the normal samples as well as tumors. Patient 4 also shows EGFR G873E on same read as L858R in the tumor samples, indicating that the two mutations are in cis. b, Phylogenetic tree from patient 6, with a germline variant identified by WES. c, Phylogenetic tree from patient 1 predicted to be independent by WES.
