Extended Data Fig. 9: Growth speed of AKPS mutant organoids and the quadruple-pathway mutant organoids. | Nature Cancer

Extended Data Fig. 9: Growth speed of AKPS mutant organoids and the quadruple-pathway mutant organoids.

From: Recapitulating the adenoma–carcinoma sequence by selection of four spontaneous oncogenic mutations in mismatch-repair-deficient human colon organoids

Extended Data Fig. 9

(a) the quadruple-pathway mutant organoids (NRASQ61K) and AKPS mutant organoids grew in complete medium (WRNE). Representative pictures from n = 3 clonal organoid lines. Scale bars, 100 µm. (b) Quantification in cell numbers of the quadruple-pathway mutant organoids (NRASQ61K) and AKPS mutant organoids Mean and SD (error bars) of n = 3 clonal organoid lines.

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