Table 1 Patient baseline and tumor characteristics

From: Efficacy and tolerability of neoadjuvant therapy with Talimogene laherparepvec in cutaneous basal cell carcinoma: a phase II trial (NeoBCC trial)

Patient baseline and tumor characteristics

 

Sex, n (%)

 Female

11 (61.1)

 Male

7 (38.9)

Age, years

 Median

74 (range 49–92)

Weight, kg

 Median

72 (range 50–145)

Height, m

 Median

1.68 (range 1.50–1.85)

ECOG (0–5)

 0

18 (100)

Skin type (Fitzpatrick)

 2

15 (83.3)

 3

3 (16.7)

Histopathological BCC subtype, n (%)

 Non-infiltrative

9 (50.0)

 Infiltrative

9 (50.0)

BCC ulceration n (%)

 Yes

9 (50.0)

 No

9 (50.0)

BCC localization, n (%)

 Head and neck

13 (72.2)

 Lower extremities

2 (11.1)

 Trunk

3 (16.7)

Longest tumor diameter, cm

 Median

1.4 (range 0.7–13.7)

Recurrent BCC, n (%)

 Yes

2 (11.1)

 No

16 (88.9)

Previous BCC surgery, n (%)

 Yes

2 (11.1)

 No

16 (88.9)

Previous BCC therapy, n (%)

 Yes

5 (27.8)

 No

13 (72.2)

Previous BCC, n (%)

 Yes

3 (16.7)

 No

15 (83.3)

Previous HSV infection, n (%)

 Yes

12 (66.7)

 No

6 (33.3)

Previous HSV lesion localization, n (%)

 Oral

11 (61.1)

 Oral and genital

1 (5.6)

 NA

6 (33.3)

Serum HSV IgG, n (%)

 Negative

1 (5.6)

 Positive

17 (94.4)

  1. Percentages are based on the number of valid values (n). Included are s.d., Eastern Cooperative Oncology Group (ECOG) performance status, BCC and HSV.