Extended Data Fig. 3: In vivo expression of inhibitory, activation and cytotoxicity receptors in DOT cells. | Nature Cancer

Extended Data Fig. 3: In vivo expression of inhibitory, activation and cytotoxicity receptors in DOT cells.

From: Dual modulation of cytotoxic and checkpoint receptors tunes the efficacy of adoptive Delta One T cell therapy against colorectal cancer

Extended Data Fig. 3

Flow cytometry density plots show representative percentages of DOT cells before infusion and in the tumor and in the blood 14 days after infusion into intercaecal SW620-bearing mice, after gating on alive human CD45+CD3+Vδ1+ cells (a) Surface markers were stained in fresh. (b) CD107a and intracellular staining were stained after 3h of PMA/Ionomycin stimulation in the presence of Brefeldin A and Monensin.

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