Extended Data Fig. 10: Receptor repertoire of endogenous Vδ1+ T cells in CRC. | Nature Cancer

Extended Data Fig. 10: Receptor repertoire of endogenous Vδ1+ T cells in CRC.

From: Dual modulation of cytotoxic and checkpoint receptors tunes the efficacy of adoptive Delta One T cell therapy against colorectal cancer

Extended Data Fig. 10

(a) Expression of TIM3 in PD1-TIGIT- and PD1+TIGIT+ Vδ1+ T cells in blood and tumors from CRC patients (connected points of n =7 patients). Data were analyzed by two-tailed paired t-test. (b) Quantification of expression of different inhibitory and cytotoxic receptors in blood from healthy controls and blood and tumors from CRC patients (n= 11 samples), represented as percentage of positive cells among alive Vδ1+ cells. Data analyzed by one-way ANOVA with Tukey’s post hoc test or Kruskal-Wallis with Dunn multiple comparisons test. Representative of three independent experiments.

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