Fig. 1: Experimental workflow and overview of the study cohort. | Nature Cancer

Fig. 1: Experimental workflow and overview of the study cohort.

From: Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of esophageal adenocarcinoma

Fig. 1

a, Flowchart summarizing patient treatment and study design, including respective neoadjuvant treatment, sample acquisition and analyses. FOLFOX, oxaliplatin and 5-FU; EOX, epirubicin, oxaliplatin and capecitabine; WES, whole-exome sequencing; RNA-seq, RNA-sequencing; IMC, imaging mass cytometry; TCR-seq, T cell receptor sequencing. b,c, Overview of the study cohort of NRPs (b) and REPs (c) with indication of samples present for each type of data analysis. Samples from different timepoints are indicated with different shapes. Age, age at diagnosis; Brg, Becker remission grade.

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