Extended Data Fig. 1: Overview of 3CA cell annotation and data summary features.

a. Dot plot showing the average expression level (colour) and percentage expressing cells (point size) of a selection of cell type marker genes (rows) in each cell type (columns) in the Raghavan et al. dataset48. b. Heatmap showing inferred copy number alteration (CNA) values (colour, quantified as log2 ratio, with blue indicating depletion and red amplification) at each chromosomal position (columns) for a representative subset of cells (rows) in the Raghavan et al. dataset48, with colour bar (left) showing the sample each cell belongs to. c. UMAP plot of all cells (points) in the Raghavan et al. dataset48, coloured by sample, with the same colours as in b.