Extended Data Fig. 3: Marker genes for each cell type in control and in K5-PTEN 6w prostate epithelial cells. | Nature Cancer

Extended Data Fig. 3: Marker genes for each cell type in control and in K5-PTEN 6w prostate epithelial cells.

From: Innate immunity and the NF-κB pathway control prostate stem cell plasticity, reprogramming and tumor initiation

Extended Data Fig. 3

Cell populations found by scRNA-seq in CTL prostate epithelial cells: (a) UMAP dimensionality reduction plots of CTL prostate epithelial cells with colors representing unsupervised clustering. (b-g) UMAP plots colored by normalized gene expression for (b) BC marker genes, (c) Proximal marker genes, (d) Ventral marker genes, (e) Lateral marker genes, (f) Antero-Dorsal marker genes and (g) Proliferative marker genes. (h) UMAP dimensionality reduction plots for K5-PTEN 6w using Seurat: UMAP dimensionality reduction plots with colors representing unsupervised clustering. (i–o) UMAP plots colored by normalized gene expression for (i) BC marker genes, (j) Proximal marker genes, (k) HY BC Prox marker genes, (l) HY Nkx3.1 marker genes, (m) Ventral marker genes, (n) Antero-Dorsal marker genes and (o) Proliferative marker genes.

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