Extended Data Fig. 1: Patient-level correlations between expression of T and NK cell-associated genes and FASLG using bulk RNA sequencing. | Nature Cancer

Extended Data Fig. 1: Patient-level correlations between expression of T and NK cell-associated genes and FASLG using bulk RNA sequencing.

From: CAR-engineered lymphocyte persistence is governed by a FAS ligand–FAS autoregulatory circuit

Extended Data Fig. 1

Correlation between CD3E, FCGR3A (the gene encoding CD16A), HBA1 (hemoglobin subunit α1), representing T, NK, and red blood cells as non-lymphocyte controls respectively, and FASLG using patient-level data obtained from The Cancer Genome Atlas (TCGA). Red line represents a simple linear regression through the data points. SKCM = skin cutaneous melanoma, BRCA = breast invasive carcinoma, OV = ovarian serous cystadenocarcinoma, PAAD = pancreatic adenocarcinoma. r = Pearson correlation coefficient, RSEM = RNA-Seq by Expectation Maximization, ns = not significant. P values calculated using a two-tailed F-test.

Source data

Back to article page