Fig. 2: Design of capture peptides and binding to cellulose.
From: Bioengineered textiles with peptide binders that capture SARS-CoV-2 viral particles
We incubated capture peptides with cellulosic materials and determined the decrease of peptide concentration in solution. a Structural models and genetic design of capture peptides AHB2-CH2, LCB1-CH2, AHB2-CEX and LCB1-CEX. Models were generated using CoLab: AlphaFold2 notebook53. b Binding of capture peptides to cellulosic materials, cotton, rayon and Avicel at pH 5 and 4 °C. Data are presented as mean and standard deviation of biological replicates and analysed using one-way ANOVA with multiple comparisons. Filled black circles show individual data points. *Significantly different to AHB2-CH2 binding to cotton at pH 5 (p < 0.01). #Significantly different to LCB1-CH2 binding to cotton at pH 5 (p < 0.01).
