Fig. 4: Sequestration of SARS-CoV-2 viral particles by bioengineered textiles.
From: Bioengineered textiles with peptide binders that capture SARS-CoV-2 viral particles
a Schematics of sequestration of SARS-CoV-2 and infection of culture cells. Unbound virus was recovered and used to infect Vero cells monolayers. Our bioengineered textile neutralises and decreases the onwards transmission of SARS-CoV-2 in cell models. b Binding of SARS-CoV-2 to bioengineered cotton, unbound capture peptides and unbound normal cotton. Infectivity of recovered unbound virus shown as log10 TCID50/mL. SARS-CoV-2 control indicated as SARS-CoV-2. c Binding of HCoV-NL63 to bioengineered cotton and unbound normal cotton. Infectivity of recovered unbound virus shown as log10 TCID50/mL. HCoV-NL63 control indicated as HCoV-NL63. TCID50/mL was calculated using the Spearman–Kaerber algorithm. Data are shown as the mean and standard deviation of six biological replicates and analysed using one-way ANOVA with multiple comparisons. Individual data points are shown as black filled circles. *Significantly different to AHB2-CH2/Cotton and LCB1-CH2/Cotton (p < 0.001). #Significantly different to AHB2-CH2 and LCB1-CH2 (p < 0.001).
