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Size-exclusion chromatography with multi-angle static light scattering

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This PrimeView demonstrates a typical benchtop SEC/MALS setup and shows the key principles of the technique, from size-exclusion-based separation to subsequent analysis of column eluate by multi-angle static light scattering.

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The PrimeView text was initially drafted using artificial intelligence, then edited by an editor to meet Nature Portfolio publication standards.

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Size-exclusion chromatography with multi-angle static light scattering. Nat Rev Methods Primers 5, 41 (2025). https://doi.org/10.1038/s43586-025-00420-z

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