Extended Data Fig. 1: The age-related loss of skeletal mass, strength, and function.
From: Characterization of cellular senescence in aging skeletal muscle
a–c, Comparisons of body weight (a), lean mass (%) (b), and quadriceps (quad) muscle weight (c) between young (n = 9) and old (n = 5) mice. d, e, Representative images of quad muscle cross-sections stained for Laminin (d) and quantification of fiber size and distribution for young and old female mice (n = 4 per group) (e). f–h, Comparison of grip strength normalized to body weight (f), treadmill exercise capacity (g), and Rotarod endurance (h) between young (n = 9) and old (n = 5) mice. Two-tailed unpaired t-test was used; error bars represent s.e.m. **, and *** denote p < 0.01 and 0.001, respectively.
