Extended Data Fig. 5: Correlations between each biomarker panel composite score and AD CSF biomarkers and cognitive function. | Nature Aging

Extended Data Fig. 5: Correlations between each biomarker panel composite score and AD CSF biomarkers and cognitive function.

From: CSF proteome profiling across the Alzheimer’s disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels

Extended Data Fig. 5

Correlation matrix heatmaps represent the Spearman’s correlation coefficient in-between the biomarker panel composite score (PC) of each of the identified CSF panels, the classical AD CSF biomarkers (Aβ42, tTau, pTau181 and tTau/Aβ42 ratio) and MMSE score in the corresponding groups for which the specific panel was built. Positive correlations are depicted in red; negative correlations are depicted in blue. Correlation coefficients are indicated. AD, Alzheimer’s disease; non-AD dem: non-AD dementias; CON, cognitively unimpaired controls.

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