Extended Data Fig. 4: Differential gene expression and pathway analysis comparison between scRNA-Seq sub-clusters identified in the HSC sub-population of total LSK cells in bone marrow of Phf6 wild-type and knockout aged mice. | Nature Aging

Extended Data Fig. 4: Differential gene expression and pathway analysis comparison between scRNA-Seq sub-clusters identified in the HSC sub-population of total LSK cells in bone marrow of Phf6 wild-type and knockout aged mice.

From: Epigenetic reversal of hematopoietic stem cell aging in Phf6-knockout mice

Extended Data Fig. 4

Network representation of gene sets enriched in the old HSC subcluster i (enriched in Phf6 knockout HSCs from old mice) and HSC subcluster ii (enriched in Phf6 wild-type HSCs from old mice). Node size indicates the number of genes in each represented gene-set. The width of the edges indicates fraction of shared genes between gene-set pairs. Data relates to Fig. 1.

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