Extended Data Fig. 8: Relationship between degree centrality and the strength of the association with Kendall Uniqueness for the different species-level taxon groups.
From: Toward an improved definition of a healthy microbiome for healthy aging
Least-square regression lines linking degree centrality measures of the different taxa and their extent of association (association coefficient) with Kendall Uniqueness. Regression-lines are shown separately for taxa belonging to each of the three different species-level-groups. For each species-group, distinct regression lines are shown separately for the co-occurrence networks obtained for each study. Panel A shows these relationships only in the study-specific co-occurrence networks derived for the gut microbiomes from older participants (participant age > = 60 years); Panel B shows the same for networks derived for younger gut microbiomes (participant age < 60 years). For both the plots, bold lines indicate the mean regression line for each of the associations, the shaded regions (in gray) corresponding to each line indicate their confidence intervals (+/- standard errors). The p-values indicated above each plot are obtained using Random Effect Models (utilizing two-sided permutation tests).
