Extended Data Fig. 9: Age-related expression changes in the mouse – additional information.

Relationship between the expression changes triggered by dfoxo-switch in the fly fat body and the expression changes caused by ageing of their mouse orthologues (FDR 10%) in the functionally equivalent organs in the mouse. Points – genes; lines with shading – line of best fit and 95% CI; grey – those that are not significantly changed with age, red – those that are significantly changed with age. None of the organs show significant correlation between age-related change and dfoxo-switch change (p > 0.05, LM).