Extended Data Fig. 4: CD38 deficiency shifted the ovarian transcriptome towards a more youthful state in 12-month-old mice. | Nature Aging

Extended Data Fig. 4: CD38 deficiency shifted the ovarian transcriptome towards a more youthful state in 12-month-old mice.

From: NADase CD38 is a key determinant of ovarian aging

Extended Data Fig. 4

a. Heatmap representation of ovarian DEGs between 12-M-old WT and Cd38−/− mice. b. and c. GO analysis identified downregulated (b) and upregulated (c) genes in enriched pathways in 12-month-old Cd38−/− mice. P values were calculated by Fisher′s Exact Test and adjusted by the Benjamini-Hochberg method. d. Heatmap showing the DEGs in cell cycle, DNA repair, inflammation, and SASP pathways in ovaries from 12-month-old WT and Cd38−/− mice.

Back to article page