Table 1 Baseline characteristics of the study population overall and by treatment group

From: Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial

Characteristic

All

Vitamin D

No vitamin D

Omega-3

No omega-3

SHEP

No SHEP

(n = 777)

(n = 397)

(n = 380)

(n = 385)

(n = 392)

(n = 388)

(n = 389)

Chronological age (years), mean (s.d.)

75.47 (4.47)

75.55 (4.54)

75.39 (4.40)

75.14 (4.20)

75.80 (4.70)

75.44 (4.48)

75.50 (4.46)

Female sex, n (%)

464 (59.7)

231 (58.2)

233 (61.3)

231 (60.0)

233 (59.4)

233 (60.1)

231 (59.4)

BMI (kg m−2), mean (s.d.)

25.72 (4.04)

25.81 (4.13)

25.63 (3.96)

25.74 (3.94)

25.70 (4.15)

25.65 (3.96)

25.80 (4.13)

Years of education, mean (s.d.)

13.48 (3.50)

13.59 (3.64)

13.37 (3.34)

13.50 (3.31)

13.47 (3.67)

13.51 (3.45)

13.46 (3.54)

Healthy ager (NHS criteria), n (%)

403 (52.3)

212 (53.9)

191 (50.5)

211 (55.2)

192 (49.4)

200 (51.9)

203 (52.6)

Sangha comorbidity score60 (0–30 points), mean (s.d.)

2.66 (2.58)

2.66 (2.54)

2.66 (2.63)

2.57 (2.63)

2.74 (2.53)

2.64 (2.65)

2.68 (2.51)

25(OH)D <20 ng ml−1, n (%)

263 (33.8)

132 (33.2)

131 (34.5)

123 (31.9)

140 (35.7)

119 (30.7)

144 (37.0)

25(OH)D (ng ml−1), mean (s.d.)

23.62 (8.44)

23.76 (8.56)

23.47 (8.31)

23.80 (8.54)

23.44 (8.33)

24.17 (8.53)

23.07 (8.32)

Blood omega-3s (DHA + EPA) <100 ng ml−1, n (%)

296 (38.1)

152 (38.3)

144 (37.9)

144 (37.4)

152 (38.8)

140 (36.1)

156 (40.1)

Blood omega-3s (DHA + EPA) (ng ml−1), mean (s.d.)

94.32 (40.12)

93.40 (40.10)

95.29 (40.17)

94.63 (39.99)

94.02 (40.30)

92.25 (38.23)

96.39 (41.87)

Physical activity, n (%)

 Inactive

93 (12.0)

50 (12.6)

43 (11.3)

45 (11.7)

48 (12.2)

38 (9.8)

55 (14.1)

 1–3 times per week

227 (29.2)

122 (30.7)

105 (27.6)

99 (25.7)

128 (32.7)

114 (29.4)

113 (29.0)

 >3 times per week

457 (58.8)

225 (56.7)

232 (61.1)

241 (62.6)

216 (55.1)

236 (60.8)

221 (56.8)

  1. NHS, Nurses’ Health Study.