Extended Data Fig. 1: Links among CpG mutations, methylome remodeling, and aging.
From: Somatic mutation as an explanation for epigenetic aging
a) Various mutational processes affect the genome. Here, we show that some of these mutations associate with an aberrant DNA methylation pattern at both the mutated site and at numerous neighboring CpGs. b) An individual’s DNA mutation profile and DNA methylation profile make similar predictions of their calendar age and rate of aging. Panel a created with BioRender.com.
