Extended Data Fig. 2: Baz2b does not affect liver phenotypes of young mice. | Nature Aging

Extended Data Fig. 2: Baz2b does not affect liver phenotypes of young mice.

From: Targeting the chromatin remodeler BAZ2B mitigates hepatic senescence and MASH fibrosis

Extended Data Fig. 2

a-c, Representative images of H&E, ORO, and Sirius red staining and αSMA immunofluorescence (a) in liver sections from 3-month-old (young) WT, Baz2b+/− and Baz2b−/− mice and their quantitative analysis (b, c). Scale bars, 50 μm. (d, e) Representative immunofluorescence staining of p16, p21, CD11b, and F4/80 in liver sections from indicated mice (d) and their quantitative analysis (e). Scale bars, 50 μm. The numbers of tested mice were indicated in parentheses. Each data point represents a value from one mouse. Data are means ± s.e.m. *P < 0.05, **P < 0.01, ***P < ns, not significant. One-way ANOVA with Dunnett’s post-test was used for (b, c, e).

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