Extended Data Fig. 4: Overlap of molecules associated with age, SMI, HGS, GS, sarcopenia, and severe sarcopenia. | Nature Aging

Extended Data Fig. 4: Overlap of molecules associated with age, SMI, HGS, GS, sarcopenia, and severe sarcopenia.

From: Sarcosine decreases in sarcopenia and enhances muscle regeneration and adipose thermogenesis by activating anti-inflammatory macrophages

Extended Data Fig. 4

a,b, Overlap analysis of molecules associated with SMI and sarcopenia (a), and severe sarcopenia (b). c,d, Overlap analysis of molecules associated with HGS and sarcopenia (c), or GS and sarcopenia (d). e,f, Overlap analysis of molecules associated with HGS and severe sarcopenia (e), or GS and severe sarcopenia (f). The sarcopenia- and severe sarcopenia-related molecules were analyzed using the Mann-Whitney U test, compared to normal individuals, with an FDR threshold of < 0.05. g, Overview of major metabolic pathways enriched by metabolites correlated with SMI and age. The coefficients of metabolites with SMI and age are represented by colors. Blue represents negative correlations, and red indicates positive correlations.

Back to article page