Extended Data Fig. 2: Assessments of metabolome and lipidome data quality in cohort1 and cohort2.

a-d, Spearman’s correlation coefficient for instrumental QC samples in the metabolomic (a,c) and lipidomic (b,d) analyses for cohort1 (a,b) and cohort2 (c,d). e-h, Relative standard deviation (RSD)% of all identified metabolites (e,g) and lipids (f,h) in instrumental QC samples for cohort1 (e,f) and cohort2 (g,h). i-l, t-SNE plots of the QCs and the samples using the metabolome (i,k) and lipidome (j,l) data of cohort1 (i,j) and cohort2 (k.l). Raw and processed data for drawing are provided in Source Data Extended Data Fig. 2.