Extended Data Fig. 6: Deregulated Pathways in GBA cohort at visit 1 and 8. | Nature Aging

Extended Data Fig. 6: Deregulated Pathways in GBA cohort at visit 1 and 8.

From: A blood-based DNA damage signature in patients with Parkinson’s disease is associated with disease progression

Extended Data Fig. 6

(a-e). Heatmaps of GSEA identified altered pathways common to visit 1 and visit 8 based on (a) Reactome, (b) KEGG, (c) Wikipathways, and (d) GO-BP. (e) Analysis against the four collections showing deregulated pathways in the GBA group exclusively at visit 1 and (f) visit 8. (g) GSEA in iPD and GBA patients focused on DNA repair pathways using the four collections reveals a different expression profile between visit 1 and visit 8.

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