Extended Data Fig. 9: The effect of RNAi of translation machinery proteins and RBPs on mitochondrial association of LARP-1 translation-mediating condensates.
From: Mitochondria-associated condensates maintain mitochondrial homeostasis and promote lifespan
a-d, Representative images (a, c) and quantification (b, d) of foci containing LARP-1::GFP-IMMTneo (indicated with scFv::BFP, purple) on mitochondria (labeled with MDH-2::mKate2, red) in the hypodermis of N2 animals treated with RNAi against the indicated translation machinery proteins (a, b) and RBPs (c, d). Scale bars, 5 μm (a, c). ≥30 animals for each group were analyzed, n = 3 independent experiments. For statistical analyses, P values were determined using one-way ANOVA (b and d). Individual data points (mean ± s.e.m.) and exact P values are shown. ***, P < 0.001.
